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配方类型:
COSMETICS AND DRUGS
配方说明:
Sustained Release Medicinals (U.S. Patent 2,793,979)
配方组成:
Lactose, USP 60 mesh/57.5
Sucrose, USP (aqueous solution: 85% (wt) sucrose to vol water/15.0
d-Amphetamine Sulfate (100%), 60-mesh/5.0
Glyceryl Distearate/25.0
配制方法:
The glyceryl distearate is melted. The d-amphetamine sulfate and lactose are mixed together and then added to the melted glyceryl distearate while stirring. After a thorough mixing of the glyceryl distearate, d-amphetamine sulfate and lactose, the mixture is cooled until it congeals to a hard mass, the stirring being continued as long as possible. This mass is ground and sieved through a #35-mesh screen.
The sucrose syrup is added to the powder thus obtained and thoroughly mixed with it to mass the powder. The resulting product is granulated through a #10-mesh screen. The granules are dried overnight at 37'C, and sieved through a #14-mesh screen.
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