配方类型:

COSMETICS AND DRUGS

配方说明:

Antibiotic Suspension

配方组成:

"Sorbo" Sorbitol Solution, USP/q.s. ad 1000.000 ml
Sodium Metabisulfite, USP/0.983 g
Citric Acid, USP (60% w/v solution)/q.s.
Propylparaben, USP/0.099 g
Cyclamate Sodium, NF/0.833 g
Color/q.s.
Calcium Dioxytetracycline/q.s.
Flavor/q.s.
Methylparaben, USP/0.899 g

配制方法:

a) blend together all solids, except the antibiotic calcium dioxytetracycline and the color, in a twin-shell blender. Pulverize these solids through a No.60 screen and reblend.
b) Add a to about 800 ml of "Sorbo" with rapid stirring, followed by the flavor.
c) Pulverize the antibiotic through a No.60 screen and add to ab. Then add the color.
d) Add sufficient "Sorbo" to bring the final volume to 1000 ml, and run the preparation through a mechanical homogenizer.
e) Adjust pH to 7.5 with a 60% w/v solution of citric acid, and saturate the preparation with nitrogen.