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配方类型:
COSMETICS AND DRUGS
配方说明:
Procaine Penicillin Suspension (U.S. Patent 2,897,120)
配方组成:
A preparation containing 300,000 units penicillin/ml, which gives
the minimum of difficulty from settling and caking
Procaine Penicillin G micronized (sterile bulk, 1.25% Lecithin)/157,500
Sodium Carboxymethyl Cellulose (Low viscosity)/5.0 mg/ml
Water for injection/q.s.
Sodium Citrate Granular USP/5.7 mg/ml
b: Procaine Penicillin G milled (sterile bulk, 4%
a: "Plasdone," Polyvinylpyrrolidone/5.0 mg/ml
Lecithin-coated)/157,500
Methylparaben USP (sterile)/2.63 mg/ml
配制方法:
To prepare the vehicle, mix the sodium citrate, sodium carboxymethylcellulose, and "Plasdone" in the water for injection and sterilize by heating to 120'C for 30 min. When cool, add the sterile methylparaben. Mix the milled and micronized penicillins and add to a under aseptic conditions. Pass the suspension through a colloid mill and fill aseptically into sterile containers.
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