配方类型:

DRUGS

配方说明:

Cough-Cold Tablet

配方组成:

Citric acid/15.0
Orange flavor/4.0
Mannitol, USP/350.0
Sodium saccharin/1.1
Binder solution (add in proportion of 235 ml for 1000 tablets)
Avicel PH/25.0
Prepare binder solution consisting o
Sorbitol (powdered)/200
Dextromethorphan hydrobromide adsorbate/150.0
Glycerin (99.5%), USP/10
Calcium stearate/10.8
Water q.s. ad/1000

配制方法:

Screen dextromethorphan hydrobromide adsorbate, mannitol, "Avicel" PH, citric acid and sodium saccharin through 40-mesh screen. Mix well.
Granulate and dry overnight at 140-150'F. Screen through 12-mesh screen.
Add flavor and calcium stearate. Mix well. compress on 7/16 inch standard concave punch to a hardness of 5-7 kg (Strong-Cobb-Arner tester).