配方类型:

DRUG PRODUCTS

配方说明:

cough-Cold Tablets (Wet Granulation)

配方组成:

Adsorbate)/150.0 mg Per Tablet
Orange Juice DF FOL MM 3X 273/4.0 mg Per Tablet
* Sorbitol (powdered): 200 g
Citric Acid/15.0 mg Per Tablet
Glycerin (99.5%) USP: 10 g
Water q.s.ad: 1000 ml
Mannitol USP/350.0 mg Per Tablet
Sodium Saccharin/1.1 mg Per Tablet
Dextromethorphan Hydrobromide (15 mg per tablet as 10%
Binder Solution* (add in proportion of 235 ml for 1000 tablets)
"Avicel" PH/25.0 mg Per Tablet
Calcium Stearate/10.8 mg

配制方法:

Screen dextromethorphan hydrobromide adsorbate, mannitol, "Avicel" PH, citric acid, and sodium saccharin through 40-mesh screen. Mix well.
Granulate and dry overnight at 140-150'F. Screen through 12-mesh screen.
Add flavor and calcium stearate. Mix well. Compress on 7/16 in. standard concave punch to a hardness of 5-7 kg (Strong-Cobb-Arner tester).