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配方类型:
DRUG PRODUCTS
配方说明:
配方组成:
magnesium stearate/2
"syloid" 266/3
"avicel" PH 101/95
starch (USP)/21
"primojel"/0
"dipac"/95
acetaminophen (granular, direct compression)/500
stearic acid (fine powder)/4
配制方法:
place acetaminophen, "avicel," "di-pac," and "syloid" in a suitable blender (P-K or ribbon mixer) and mix for 20 min (run intensifier bar for two 1-min periods at the 9-and 19-min points). add starch or "primojel" and lubricants and mix for 10 min.
tableting: tablets are compressed on oval-shaped tooling (1/4 in. ? 5/8 in.) on a manesty rotapress with forced feed and 45 stations.
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