配方类型:

DRUGS

配方说明:

Griseofulvin 250 mg Tablet

配方组成:

Emdex/60.00 mg/Tablet
Lactose/100.00 mg/Tablet
Griseofulvin (micronized)/250.00 mg/Tablet
Avicel PH 101/115.00 mg/Tablet
Stearic acid/6.00 mg/Tablet
Starch paste (30% W/V)/10.00 mg/Tablet
VEEGUM F/50.00 mg/Tablet
Cab-O-Sil M-7/9.00 mg/Tablet

配制方法:

Prepare a wet granulation of griseofulvin. Mix the griseofulvin, lactose and starch paste and pass through a 14 mesh sieve. Dry the granules in a 60'C oven for 6 hours. Collect granules passing through a 20 mesh sieve. Combine griseofulvin granules, VEEGUM F, Emdex and Avicel PH 101 and mix for 15 minutes. Add the stearic acid and Cab-O-Sil to the mixture and blend for an additional 10 minutes. Compress.