联系我们
售前服务：
15684008065 张经理
售后服务：
18510452922 樊经理
技术服务：
18188974168 谢经理
投诉建议：
0535-2166036
A solution of 14 g (00.33 mol) of N-[3-(diethylamino)propyl]-4-(4-methoxyphenyl)-5-phenyl-1H-pyrazole-1-acetamide of example 34 and 0.16 mol of the sodium salt of 1 propanethiol in 375 mL of DMF was heated at 155°-160° C. for 2 hours. The reaction was chilled and the excess thiopropoxide was neutralized with ethanolic HCl. The DMF solution was stripped under vacuum at 30°, dissolved in methylene dichloride, and washed with aqueous sodium carbonate, then water, and finally brine. The methylene ch
| 产品 | N-[3-(Diethylamino)propyl]-4-(4-hydroxyphenyl)-5-phenyl-1H-pyrazole-1-acetamide |
| 反应物 |
N-[3-(diethylamino)propyl]-4-(4-methoxyphenyl)-5-phenyl-1H-pyrazole-1-acetamide sodium n-propanethiol thiopropoxide hydrochloric acid |
| 试剂 |
dimethylformamide methylene chloride dimethylformamide |
| 程序 |
1、Heat A solution of 14 g (00.33 mol) of N-[3-(diethylamino)propyl]-4-(4-methoxyphenyl)-5-phenyl-1H-pyrazole-1-acetamide of example 34 and 0.16 mol of the sodium salt of 1 propanethiol in 375 mL of DMF was heated at 155°-160° C. for 2 hours 2、Cool The reaction was chilled 3、Unknown was stripped under vacuum at 30° 4、Dissolve dissolved in methylene dichloride 5、Wash washed with aqueous sodium carbonate 6、Dry The methylene chloride was dried over sodium sulfate 7、Remove the solvent removed in vacuo 8、Yield to yield 13.4 g of gummy product |
角色：product
分类：产品
实体类型：exact
角色：reactant
分类：原料
实体类型：definiteReference
角色：reactant
分类：原料
实体类型：definiteReference
角色：reactant
分类：原料
实体类型：exact
角色：reactant
分类：原料
实体类型：definiteReference
角色：reactant
分类：原料
实体类型：exact
角色：solvent
分类：催化剂
实体类型：exact
角色：solvent
分类：催化剂
实体类型：exact
角色：solvent
分类：催化剂
实体类型：exact